Retinoids: Topical

Retinoids are a class of medications derived from vitamin A that are used for a variety of skin conditions, including acne, aging skin, and psoriasis.

Topical retinoids are designed to be applied to the skin. They include:

• Adapalene (Differin)
• Tazarotene (Tazorac)
• Tretinoin (Retin A Micro, generic)

Topical retinoids have become one of the primary components of acne management because of their unique ability to open clogged pores. They may be combined with other treatments, such as antibiotics.

Clinical studies of topical retinoids have also shown them to be effective in diminishing fine lines and superficial wrinkles. They may slow down the onset of wrinkles and extend the time between other treatments.

All topical retinoids are safe and effective, but there are several common side effects, including skin dryness and irritation. This is usually worse during the first few weeks of treatment.

Topical retinoids can also increase your sensitivity to ultraviolet (UV) light. If you use a topical retinoid, you should also use a sunscreen with SPF of at least 15 to prevent additional skin irritation.

Topical retinoids are usually prescribed for use once per day, at night. The use at night is recommended because the sun’s UV radiation can deactivate the medication.